Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T
A Phase I trial to determine the safety of targeted immunotherapy with daratumumab (DARA) IV after total body irradiation (TBI)-based myeloablative conditioning and allogeneic hematopoietic cell transplantation (HCT) for children, adolescents, and鈥�
- Investigator
- Jordan Milner
- Status
- Accepting Candidates
- Ages
- N/A - 39 Years
- Sexes
- All
Alpha/beta T cell and CD19+ B cell depletion in Allogeneic Stem Cell Transplantation
This study will assess the safety, efficacy, and feasibility of 鈲�/尾 CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), juvenile鈥�
- Investigator
- Jordan Milner
- Status
- Accepting Candidates
- Ages
- 6 Months - 39 Years
- Sexes
- All
NYMC-571
This is a follow-up trial to NYMC 526 (NCT01461837) to assess the safety, efficacy and toxicity of administering Defibrotide prophylaxis for high-risk sickle cell or beta thalassemia patients undergoing a familial haploidentical allogeneic stem cell鈥�
- Investigator
- Jordan Milner
- Status
- Accepting Candidates
- Ages
- 6 Months - 34 Years
- Sexes
- All