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Jennifer L Miller, MD : Research

Pediatric Endocrinologist (Child Hormone Specialist)

Photo of Jennifer L Miller

Research at a glance

Top areas of exploration

  • Prader-Willi Syndrome , 48 publications
  • Hyperphagia , 8 publications
  • Chromosomes, Human, Pair 15 , 8 publications
  • Obesity , 7 publications

Research activity

68 publications

3,175 citations

Why is this important?

Focus

My research focuses on investigation of the etiology and possible treatment for obesity and metabolic abnormalities in individuals with Prader-Willi syndrome and early-onset obesity. I have been working towards achieving an appropriate treatment for hyperphagia for the past 12 years. I currently follow over 500 patients with Prader-Willi syndrome from around the world, and over 100 patients with early-onset obesity due to other genetic causes. I am working on clinical treatment trials to treat hyperphagia in individuals with Prader-Willi syndrome and early-onset obesity..

Active clinical trials

TRYP-001

To better understand the potential benefits of psychedelics in overeating disorders, Tryp Therapeutics will conduct a safety and feasibility clinical trial using TRP 8802 among individuals with Binge Eating Disorder. This is a single-center phase 2a鈥�

Investigator
Jennifer L Miller
Status
Accepting Candidates
Ages
18 Years - 64 Years
Sexes
All
HBS-101-CL-002

The primary objective of this study is to evaluate the safety and efficacy of pitolisant compared with placebo in treating excessive daytime sleepiness (EDS) in patients with Prader Willi syndrome (PWS) ages 6 to 65 years.

Investigator
Jennifer L Miller
Status
Accepting Candidates
Ages
6 Years - 65 Years
Sexes
All

My publications

68 publications

2023

Intranasal Carbetocin Reduces Hyperphagia, Anxiousness, and Distress in Prader-Willi Syndrome: CARE-PWS Phase 3 Trial.

The Journal of clinical endocrinology and metabolism

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2023

The Arduous Path to Drug Approval for the Management of Prader-Willi Syndrome: A Historical Perspective and Call to Action.

International journal of molecular sciences

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2022

Critical review of bariatric surgical outcomes in patients with Prader-Willi syndrome and other hyperphagic disorders.

Obesity (Silver Spring, Md.)

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2022

Molecular Classes and Growth Hormone Treatment Effects on Behavior and Emotion in Patients with Prader-Willi Syndrome.

Journal of clinical medicine

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2022

The Efficacy, Safety, and Pharmacology of a Ghrelin O-Acyltransferase Inhibitor for the Treatment of Prader-Willi Syndrome.

The Journal of clinical endocrinology and metabolism

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