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This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with鈥�

Investigator

Brian Stover

Status

Accepting Candidates

Ages

N/A - 30 Years

Sexes

All

This phase III trial compares memantine to placebo in treating patients with primary central nervous system tumors. Memantine may block receptors (parts of nerve cells) in the brain known to contribute to a decline in cognitive function. Giving鈥�

Investigator

Brian Stover

Status

Accepting Candidates

Ages

4 Years - 17 Years

Sexes

All

This phase III trial compares the effects of nivolumab with chemo-immunotherapy versus chemo-immunotherapy alone in treating patients with newly diagnosed primary mediastinal B-cell lymphoma (PMBCL). Immunotherapy with monoclonal antibodies, such as鈥�

Investigators

Brian Stover, William Slayton

Status

Accepting Candidates

Ages

2 Years - N/A

Sexes

All