Bently P Doonan, MD - Research

Research at a glance

Top areas of exploration

Antigen Presentation , 4 publications
Melanoma , 3 publications
CD4-Positive T-Lymphocytes , 3 publications
Autophagy , 3 publications

Research activity

18 publications

328 citations

Why is this important?

Active clinical trials

Oral IRAK-4 inhibitor CA-4948 in combination with Pembrolizumab following stereotactic radiosurgery

This phase I/II trial will investigate the use of the novel oral IRAK-4 inhibitor CA-4948 in combination with pembrolizumab therapy following stereotactic radiosurgery in patients with melanoma brain metastases (MBM). The investigators hypothesize鈥�

Investigator: Bently P Doonan
Status: Accepting Candidates
Ages: 18 Years - 99 Years
Sexes: All

My publications

18 publications

2018

Autophagy-dependent crosstalk between GILT and PAX-3 influences radiation sensitivity of human melanoma cells.

Journal of cellular biochemistry

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2015

Prostate Cancer Immunotherapy: Exploiting the HLA Class II Pathway in Vaccine Design.

Journal of clinical & cellular immunology

2012

A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma.

Apoptosis : an international journal on programmed cell death

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2012

Mechanisms regulating enhanced human leukocyte antigen class II-mediated CD4 + T cell recognition of human B-cell lymphoma by resveratrol.

Leukemia & lymphoma

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2011

Regulation of Th1/Th17 cytokines and IDO gene expression by inhibition of calpain in PBMCs from MS patients.

Journal of neuroimmunology

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BOB体育

Bently P Doonan, MD : Research

Research at a glance

Top areas of exploration

Research activity

Active clinical trials

My publications

Autophagy-dependent crosstalk between GILT and PAX-3 influences radiation sensitivity of human melanoma cells.

Prostate Cancer Immunotherapy: Exploiting the HLA Class II Pathway in Vaccine Design.

A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma.

Mechanisms regulating enhanced human leukocyte antigen class II-mediated CD4 + T cell recognition of human B-cell lymphoma by resveratrol.

Regulation of Th1/Th17 cytokines and IDO gene expression by inhibition of calpain in PBMCs from MS patients.

BOB体育

Research at a glance

Top areas of exploration

Research activity

Active clinical trials

My publications

Filter publications

Autophagy-dependent crosstalk between GILT and PAX-3 influences radiation sensitivity of human melanoma cells.

Prostate Cancer Immunotherapy: Exploiting the HLA Class II Pathway in Vaccine Design.

A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma.

Mechanisms regulating enhanced human leukocyte antigen class II-mediated CD4 + T cell recognition of human B-cell lymphoma by resveratrol.

Regulation of Th1/Th17 cytokines and IDO gene expression by inhibition of calpain in PBMCs from MS patients.